BDBM50075519 4,6-Di-tert-butyl-2-(5-methylsulfanyl-[1,3,4]thiadiazol-2-yl)-pyrimidin-5-ol::CHEMBL275188

SMILES CSc1nnc(s1)-c1nc(c(O)c(n1)C(C)(C)C)C(C)(C)C

InChI Key InChIKey=UHAUUAGUJDZJLR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075519   

TargetProstaglandin G/H synthase 2(Mouse)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075519(4,6-Di-tert-butyl-2-(5-methylsulfanyl-[1,3,4]thiad...)
Affinity DataIC50: 26nMAssay Description:IC50 value against Prostaglandin G/H synthase 2 of murine J774A.1 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075519(4,6-Di-tert-butyl-2-(5-methylsulfanyl-[1,3,4]thiad...)
Affinity DataIC50: 97nMAssay Description:IC50 value against ovine Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075519(4,6-Di-tert-butyl-2-(5-methylsulfanyl-[1,3,4]thiad...)
Affinity DataIC50: 200nMAssay Description:IC50 value against Prostaglandin G/H synthase 1 of human platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075519(4,6-Di-tert-butyl-2-(5-methylsulfanyl-[1,3,4]thiad...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed