BDBM50075681 CHEMBL3415586

SMILES Cc1cc(C)nc(Nc2cc(NC[C@@H](N)C(F)(F)F)cnc2C(N)=O)c1

InChI Key InChIKey=FDIMKCQGUSVISE-GFCCVEGCSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50075681   

TargetTyrosine-protein kinase SYK(Human)
Merck

Curated by ChEMBL

LigandBDBM50075681(CHEMBL3415586)Copy SMILESCopy InChI

Affinity DataIC50:  371nMAssay Description:Inhibition of full-length GST-tagged human Syk preincubated for 10 mins followed by peptide substrate/ATP addition measured after 45 mins by TR-FRET ...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50075681(CHEMBL3415586)Copy SMILESCopy InChI

Affinity DataIC50:  4.20E+4nMAssay Description:Displacement of radio-labeled MK-499 from ERG channel in human embryonic kidney cellsMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL