BDBM50075741 CHEMBL3415591

SMILES Cc1cc(C)nc(Nc2cc(NC[C@@H](N)CCS(C)(=O)=O)cnc2C(N)=O)c1

InChI Key InChIKey=VLNPTNLCXAVWMC-ZDUSSCGKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50075741   

LigandPNGBDBM50075741(CHEMBL3415591)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of ERG channel expressed in human embryonic kidney cells assessed as tail current amplitude measured for 3 to 30 mins by PatchXpress elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase SYK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50075741(CHEMBL3415591)
Affinity DataIC50:  5nMAssay Description:Inhibition of full-length GST-tagged human Syk preincubated for 10 mins followed by peptide substrate/ATP addition measured after 45 mins by TR-FRET ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed