BDBM50075789 4-[3-(4-Fluoro-phenyl)-1H-pyrrol-2-yl]-pyridine::CHEMBL160314

SMILES Fc1ccc(cc1)-c1cc[nH]c1-c1ccncc1

InChI Key InChIKey=RRGXAHXPWSPEEU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075789   

TargetMitogen-activated protein kinase 14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075789(4-[3-(4-Fluoro-phenyl)-1H-pyrrol-2-yl]-pyridine | ...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against p38-alpha kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)TBA
LigandPNGBDBM50075789(4-[3-(4-Fluoro-phenyl)-1H-pyrrol-2-yl]-pyridine | ...)
Affinity DataIC50: 160nMAssay Description:Antagonist activity at human glucagon receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article

TargetGlucagon receptor(Human)TBA
LigandPNGBDBM50075789(4-[3-(4-Fluoro-phenyl)-1H-pyrrol-2-yl]-pyridine | ...)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]glucagon to the human glucagon receptor (GGR) expressed on CHO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)TBA
LigandPNGBDBM50075789(4-[3-(4-Fluoro-phenyl)-1H-pyrrol-2-yl]-pyridine | ...)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]glucagon to the human glucagon receptor (GGR) expressed on CHO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed