BDBM50075881 4-[2,2-Dimethyl-4-(5-methyl-thiophen-2-yl)-2H-1-thia-anthracen-6-yl]-benzoic acid::CHEMBL163223

SMILES Cc1ccc(s1)C1=CC(C)(C)Sc2cc3ccc(cc3cc12)-c1ccc(cc1)C(O)=O

InChI Key InChIKey=CXYNRDWVVCAQRD-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075881   

TargetRetinoic acid receptor beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50075881(4-[2,2-Dimethyl-4-(5-methyl-thiophen-2-yl)-2H-1-th...)
Affinity DataKd:  13nMAssay Description:Antagonistic activity against RAR beta in transcriptional activation assay with 10 nM TTNPBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor alpha(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50075881(4-[2,2-Dimethyl-4-(5-methyl-thiophen-2-yl)-2H-1-th...)
Affinity DataKd:  13nMAssay Description:Antagonistic activity against RAR alpha in transcriptional activation assay with 32 nM TTNPBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50075881(4-[2,2-Dimethyl-4-(5-methyl-thiophen-2-yl)-2H-1-th...)
Affinity DataKd:  18nMAssay Description:Antagonistic activity against RAR gamma in transcriptional activation assay with 3.2 nM TTNPBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed