BDBM50075951 CHEMBL3415810

SMILES Cl.CN(CC#C)CC(=C)c1ccccc1

InChI Key InChIKey=BRLIOTJQBXTUFB-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50075951   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
A* Star

Curated by ChEMBL
LigandPNGBDBM50075951(CHEMBL3415810)
Affinity DataKi:  60nMAssay Description:Binding affinity to human recombinant MAO-B measured after longer preincubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
A* Star

Curated by ChEMBL
LigandPNGBDBM50075951(CHEMBL3415810)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant MAO-A expressed in Sf9 cells using 5-hydroxytryptamine substrate assessed as hydrogen peroxide production after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
A* Star

Curated by ChEMBL
LigandPNGBDBM50075951(CHEMBL3415810)
Affinity DataIC50:  50nMAssay Description:Inhibition of rat brain MAO-A in nuclei-free homogenates using [14C]hydroxytryptamine substrate after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
A* Star

Curated by ChEMBL
LigandPNGBDBM50075951(CHEMBL3415810)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human recombinant MAO-B expressed in Sf9 cells using 5-phenylacetaldehyde substrate assessed as hydrogen peroxide production after 1 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
A* Star

Curated by ChEMBL
LigandPNGBDBM50075951(CHEMBL3415810)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of rat brain MAO-B in nuclei-free homogenates using [14C]phenylacetaldehyde substrate after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed