BDBM50076067 1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro-5-pyridinyl]-2-[4-(2-cyclohexylethyl)-3-methylsulfonamido-2-oxo-1,2-dihydro-1-pyridinyl]acetamide::CHEMBL170338

SMILES CS(=O)(=O)Nc1c(CCC2CCCCC2)ccn(CC(=O)N[C@H]2CCCN(C2O)C(N)=N)c1=O

InChI Key InChIKey=XARBHAVVGPUFRH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50076067   

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076067(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 256nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076067(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 257nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076067(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Plasmin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076067(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Factor Xa cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed