BDBM50076071 1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro-5-pyridinyl]-2-[2-oxo-4-phenethyl-3-(2,2,2-trifluoroethylsulfonamido)-1,2-dihydro-1-pyridinyl]acetamide::CHEMBL414832

SMILES NC(=N)N1CCC[C@H](NC(=O)Cn2ccc(CCc3ccccc3)c(NS(=O)(=O)CC(F)(F)F)c2=O)C1O

InChI Key InChIKey=QZQQGWLVAUEZSU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50076071   

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076071(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 194nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076071(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 1.22E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076071(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Factor Xa cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076071(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Plasmin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed