BDBM50076163 2-biphenyl-4-yl-N-tert-butyl-2-[(3R,6S)-3-mercaptomethyl-6-(4-nitro-benzyl)-2,5-dioxo-piperazin-1-yl]-acetamide::CHEMBL280824

SMILES CC(C)(C)NC(=O)C(N1[C@@H](Cc2ccc(cc2)[N+]([O-])=O)C(=O)N[C@@H](CS)C1=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=NZTYUHZJGSVXFH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50076163   

TargetInterstitial collagenase(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50076163(2-biphenyl-4-yl-N-tert-butyl-2-[(3R,6S)-3-mercapto...)
Affinity DataIC50: 102nMAssay Description:Inhibitory activity against Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50076163(2-biphenyl-4-yl-N-tert-butyl-2-[(3R,6S)-3-mercapto...)
Affinity DataIC50: 102nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50076163(2-biphenyl-4-yl-N-tert-butyl-2-[(3R,6S)-3-mercapto...)
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50076163(2-biphenyl-4-yl-N-tert-butyl-2-[(3R,6S)-3-mercapto...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibitory activity against Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed