BDBM50076396 2-(4-Methyl-piperazin-1-yl)-indeno[1,2,3-de]quinoline::CHEMBL43512

SMILES CN1CCN(CC1)c1cc2-c3ccccc3-c3cccc(n1)c23

InChI Key InChIKey=XTTQFLVFNCITLP-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50076396   

Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50076396(2-(4-Methyl-piperazin-1-yl)-indeno[1,2,3-de]quinol...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor (5-HT 3 receptor) of rat cortex and hippocampus tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50076396(2-(4-Methyl-piperazin-1-yl)-indeno[1,2,3-de]quinol...)
Affinity DataKi:  640nMAssay Description:Binding affinity against 5-hydroxytryptamine 1B receptor of rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50076396(2-(4-Methyl-piperazin-1-yl)-indeno[1,2,3-de]quinol...)
Affinity DataKi:  1.60E+3nMAssay Description:Binding affinity towards Serotonin transporter was determined in rat forebrain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50076396(2-(4-Methyl-piperazin-1-yl)-indeno[1,2,3-de]quinol...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptor of rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50076396(2-(4-Methyl-piperazin-1-yl)-indeno[1,2,3-de]quinol...)
Affinity DataKi:  1.30E+4nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor of rat pre-frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50076396(2-(4-Methyl-piperazin-1-yl)-indeno[1,2,3-de]quinol...)
Affinity DataKi:  2.40E+4nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor of rat hippocampus tissue.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed