BDBM50076640 CHEMBL173133::N-Hydroxy-N-{3-[1-(4-methoxy-phenyl)-5-p-tolyl-1H-pyrazol-3-yl]-prop-2-ynyl}-propionamide

SMILES CCC(=O)N(O)CC#Cc1cc(-c2ccc(C)cc2)n(n1)-c1ccc(OC)cc1

InChI Key InChIKey=RKRQDQOBOLUBQU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50076640   

TargetProstaglandin G/H synthase 1/2(RAT)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50076640(CHEMBL173133 | N-Hydroxy-N-{3-[1-(4-methoxy-phenyl...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against cyclooxygenase (COX) in intact rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50076640(CHEMBL173133 | N-Hydroxy-N-{3-[1-(4-methoxy-phenyl...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase (5-LO) in intact rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed