BDBM50076853 2-(2-Chloro-phenyl)-4-(3-fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-thiazole::CHEMBL279752

SMILES CS(=O)(=O)c1ccc(cc1)-c1sc(nc1-c1cccc(F)c1)-c1ccccc1Cl

InChI Key InChIKey=WKZPKGNJWJXPNK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50076853   

TargetProstaglandin G/H synthase 2(Human)
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076853(2-(2-Chloro-phenyl)-4-(3-fluoro-phenyl)-5-(4-metha...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human cyclooxygenase-2 (hCOX-2) enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076853(2-(2-Chloro-phenyl)-4-(3-fluoro-phenyl)-5-(4-metha...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human cyclooxygenase-1 (hCOX-1) enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed