BDBM50077243 CHEMBL53637::N-[4-(3-Chloro-phenylamino)-quinazolin-6-yl]-acrylamide

SMILES Clc1cccc(Nc2ncnc3ccc(NC(=O)C=C)cc23)c1

InChI Key InChIKey=UKQXWBMAVBHAKP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077243   

TargetEpidermal growth factor receptor(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077243(N-[4-(3-Chloro-phenylamino)-quinazolin-6-yl]-acryl...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of phosphorylation of glutamic acid/tyrosine random copolymer by isolated epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077243(N-[4-(3-Chloro-phenylamino)-quinazolin-6-yl]-acryl...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of epidermal growth factor receptor in A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed