BDBM50077364 CHEMBL56158::[(R)-6-tert-Butoxycarbonylamino-2-(4'-fluoro-biphenyl-4-sulfonyl)-1,2,3,4-tetrahydro-isoquinolin-3-yl]-oxo-acetic acid

SMILES CC(C)(C)OC(=O)Nc1ccc2CN([C@H](Cc2c1)C(=O)C(O)=O)S(=O)(=O)c1ccc(cc1)-c1ccc(F)cc1

InChI Key InChIKey=LERSXUYNVGTZOT-XMMPIXPASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50077364   

TargetNeutrophil collagenase(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077364(CHEMBL56158 | [(R)-6-tert-Butoxycarbonylamino-2-(4...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed