BDBM50077394 CHEMBL294426::[(R)-2-(4'-Fluoro-biphenyl-4-sulfonyl)-3-hydroxycarbamoyl-1,2,3,4-tetrahydro-isoquinolin-7-yl]-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)Nc1ccc2C[C@@H](N(Cc2c1)S(=O)(=O)c1ccc(cc1)-c1ccc(F)cc1)C(=O)NO

InChI Key InChIKey=IGRVUOPMHNISAV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50077394   

TargetNeutrophil collagenase(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077394([(R)-2-(4'-Fluoro-biphenyl-4-sulfonyl)-3-hydroxyca...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed