BDBM50077636 (6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-3,6-diaza-benzo[c]phenanthrene-10,11-diol::CHEMBL284644

SMILES Oc1cc2CC[C@H]3NCc4cnccc4[C@@H]3c2cc1O

InChI Key InChIKey=USNRFQBPPPITNX-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077636   

TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50077636((6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-3,6-diaza-benz...)
Affinity DataEC50:  38nMAssay Description:Binding affinity to Dopamine receptor D1 by using radioligand [125I]SCH-23982 in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50077636((6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-3,6-diaza-benz...)
Affinity DataKi:  140nMAssay Description:Binding affinity to Dopamine receptor D1 by using radioligand [125I]SCH-23982 in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50077636((6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-3,6-diaza-benz...)
Affinity DataKi:  4.40E+3nMAssay Description:Binding affinity to human Dopamine receptor D2 by using radioligand [3H]spiperone in LTK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed