BDBM50077638 (6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-4,6-diaza-benzo[c]phenanthrene-10,11-diol::CHEMBL281932

SMILES Oc1cc2CC[C@H]3NCc4ncccc4[C@@H]3c2cc1O

InChI Key InChIKey=ZFSVGJPKLUWVIK-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077638   

TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50077638((6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-4,6-diaza-benz...)
Affinity DataEC50:  6.70nMAssay Description:Binding affinity to Dopamine receptor D1 by using radioligand [125I]SCH-23982 in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50077638((6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-4,6-diaza-benz...)
Affinity DataKi:  65nMAssay Description:Binding affinity to Dopamine receptor D1 by using radioligand [125I]SCH-23982 in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50077638((6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-4,6-diaza-benz...)
Affinity DataKi:  2.50E+3nMAssay Description:Binding affinity to human Dopamine receptor D2 by using radioligand [3H]spiperone in LTK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed