BDBM50077819 3-[3-(4-Benzyloxy-piperidin-1-yl)-2,2-difluoro-propyl]-5-[1,2,4]triazol-4-yl-1H-indole::CHEMBL63258

SMILES FC(F)(CN1CCC(CC1)OCc1ccccc1)Cc1c[nH]c2ccc(cc12)-n1cnnc1

InChI Key InChIKey=OZJBTWVMOLMZSS-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50077819   

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077819(3-[3-(4-Benzyloxy-piperidin-1-yl)-2,2-difluoro-pro...)
Affinity DataEC50:  34nMAssay Description:Agonist-induced [35S]-GTP-gammaS, binding in CHO cells stably transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077819(3-[3-(4-Benzyloxy-piperidin-1-yl)-2,2-difluoro-pro...)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist-induced [35S]-GTP-gammaS, binding in CHO cells stably transfected with human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077819(3-[3-(4-Benzyloxy-piperidin-1-yl)-2,2-difluoro-pro...)
Affinity DataIC50:  8.5nMAssay Description:Displacement of specific [3H]-5-HT binding to cloned human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077819(3-[3-(4-Benzyloxy-piperidin-1-yl)-2,2-difluoro-pro...)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of specific [3H]-5-HT binding to cloned human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed