BDBM50077943 3-Benzo[1,3]dioxol-5-yl-4-[3-(3-dimethylamino-propoxy)-4,5-dimethoxy-benzyl]-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL68269

SMILES COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OCCCN(C)C)c1)c1ccc2OCOc2c1

InChI Key InChIKey=CQVCPSUMZXOSTH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077943   

TargetEndothelin receptor type B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50077943(3-Benzo[1,3]dioxol-5-yl-4-[3-(3-dimethylamino-prop...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin B receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50077943(3-Benzo[1,3]dioxol-5-yl-4-[3-(3-dimethylamino-prop...)
Affinity DataIC50:  1nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed