BDBM50078044 3-(6-Chloro-pyridin-3-ylmethyl)-3H-thiazol-(2E)-ylideneamine::3-(6-Chloro-pyridin-3-ylmethyl)-3H-thiazol-2-ylideneamine::CHEMBL72675
SMILES Clc1ccc(Cn2ccsc2=N)cn1
InChI Key InChIKey=RLSQXMJPNPUPPZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50078044
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataKi: 0.390nMAssay Description:Potency to displace [3H]-Nicotine binding to Nicotinic acetylcholine receptor alpha4-beta2 immuno-isolated from M10 cellsMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit beta-like 2(Fruit fly)
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 185nMAssay Description:Inhibition of [3H]IMI binding to Drosophila melanogaster neuronal acetylcholine receptorMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of [3H]alpha-BGT binding to alpha7 nicotinic acetylcholine receptor in Homo sapiens (human) SH-SY5Y cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of [3H]alpha-BGT binding to alpha1 nicotinic acetylcholine receptor in Homo sapiens (human) TE671 cells co-expressing gammaalpha1deltabeta...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 0.910nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Mouse)
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of [3H]nicotine binding to alpha4 nicotinic acetylcholine receptor in Mus musculus (mouse) M10 cells co-expressing beta2 nicotinic acetylc...More data for this Ligand-Target Pair