BDBM50078393 (S)-1-[(S)-1-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-butyryl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carboxylic acid {(S)-1-[(S)-1-((R)-1-carbamoyl-2-mercapto-ethylcarbamoyl)-ethylcarbamoyl]-ethyl}-amide::CHEMBL78505

SMILES C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(=O)N[C@@H](CS)C(N)=O

InChI Key InChIKey=NZQDJXSJXCVXAN-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50078393   

TargetCytosol aminopeptidase(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078393((S)-1-[(S)-1-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-b...)
Affinity DataIC50: 290nMAssay Description:Inhibition against Leucyl aminopeptidase from pig kidney.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetXaa-Pro aminopeptidase 2(Rat)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078393((S)-1-[(S)-1-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-b...)
Affinity DataIC50: 660nMAssay Description:Activity against membrane bound rat aminopeptidase PMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetXaa-Pro aminopeptidase 1(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078393((S)-1-[(S)-1-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-b...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition against cytosolic Aminopeptidase P from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetXaa-Pro aminopeptidase 2(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078393((S)-1-[(S)-1-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-b...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition against membrane bound human aminopeptidase PMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetXaa-Pro aminopeptidase 2(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078393((S)-1-[(S)-1-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-b...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition against membrane bound monkey aminopeptidase PMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetXaa-Pro aminopeptidase 1(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078393((S)-1-[(S)-1-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-b...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition against Aminopeptidase P from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetXaa-Pro dipeptidase(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078393((S)-1-[(S)-1-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-b...)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition against Prolidase from pig kidney.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed