BDBM50078550 CHEMBL295211::[(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-2-oxo-3,3a,8,8a-tetrahydro-2H-indeno[2,1-b]pyrrol-1-yl]-acetic acid methyl ester

SMILES COC(=O)CN1[C@H]2Cc3ccccc3[C@@H]2[C@@H](CCCCC(N)=N)C1=O

InChI Key InChIKey=PJNIJOHEXAJXHR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078550   

TargetProthrombin(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50078550([(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-2-oxo-3,3a...)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50078550([(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-2-oxo-3,3a...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50078550([(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-2-oxo-3,3a...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed