BDBM50078551 CHEMBL46365::[(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-6-(3-diethylcarbamoyl-phenyl)-2-oxo-3,3a,8,8a-tetrahydro-2H-indeno[2,1-b]pyrrol-1-yl]-phosphonic acid diethyl ester

SMILES CCOP(=O)(OCC)N1[C@H]2Cc3cc(ccc3[C@@H]2[C@@H](CCCCC(N)=N)C1=O)-c1cccc(c1)C(=O)N(CC)CC

InChI Key InChIKey=GNOYEZXDZMTHAR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078551   

TargetSerine protease 1(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50078551([(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-6-(3-dieth...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50078551([(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-6-(3-dieth...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50078551([(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-6-(3-dieth...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed