BDBM50078872 CHEMBL3416353

SMILES COC1=CC(=O)C(OC)=C(C/C=C(\C)CC/C=C(\C)CCC=C(C)C)C1=O

InChI Key InChIKey=FURKCAPXNNDCBH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50078872   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50078872BDBM50078872(CHEMBL3416353)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed
TargetMacrophage-expressed gene 1 protein(Human)
University of Naples

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50078872BDBM50078872(CHEMBL3416353)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mPGES1 in IL-1beta stimulated human A549 cell microsomal membranes assessed as reduction in PGE2 synthase activity after 15 mins using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed