BDBM50079754 CHEMBL65476::N*3*-Cyclopropyl-7-(4-isopropyl-benzyl)-N*3*-methyl-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine

SMILES CC(C)c1ccc(Cn2ccc3c2ccc2nc(nc(N)c32)N(C)C2CC2)cc1

InChI Key InChIKey=MNFAOEQXSOWASB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079754   

TargetProteinase-activated receptor 1(Human)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50079754(N*3*-Cyclopropyl-7-(4-isopropyl-benzyl)-N*3*-methy...)
Affinity DataIC50: 52nMAssay Description:Antagonist activity at PAR1 in human platelet membranes assessed as inhibition of interaction of PAR1 with [Ala-Phe(p-F)-Arg-Cha-HArg-Tyr-NH2] by Chr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50079754(N*3*-Cyclopropyl-7-(4-isopropyl-benzyl)-N*3*-methy...)
Affinity DataIC50: 52nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed