BDBM50079812 (S)-2-{[(2S,4R)-1-((E)-(R)-4-Amino-5-mercapto-pent-2-enyl)-4-phenoxy-pyrrolidine-2-carbonyl]-amino}-4-methylsulfanyl-butyric acid with di( TFA)::CHEMBL63663

SMILES CSCC[C@H](NC(=O)[C@@H]1C[C@H](CN1C\C=C\[C@@H](N)CS)Oc1ccccc1)C(O)=O

InChI Key InChIKey=GZFFUOZMNSMHSN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079812   

LigandPNGBDBM50079812((S)-2-{[(2S,4R)-1-((E)-(R)-4-Amino-5-mercapto-pent...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50079812((S)-2-{[(2S,4R)-1-((E)-(R)-4-Amino-5-mercapto-pent...)
Affinity DataIC50: 8.00E+3nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed