BDBM50080080 3-(1-Cyclopropyl-ethoxy)-4-(4-methanesulfonyl-phenyl)-5,5-dimethyl-5H-furan-2-one::CHEMBL305507

SMILES CC(OC1=C(c2ccc(cc2)S(C)(=O)=O)C(C)(C)OC1=O)C1CC1

InChI Key InChIKey=WTOORHANEMAYPO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50080080   

TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080080(3-(1-Cyclopropyl-ethoxy)-4-(4-methanesulfonyl-phen...)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080080(3-(1-Cyclopropyl-ethoxy)-4-(4-methanesulfonyl-phen...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080080(3-(1-Cyclopropyl-ethoxy)-4-(4-methanesulfonyl-phen...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibitory activity against Human Cyclooxygenase-1 ( COX-1 ) in U937 Microsome COX-1 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed