BDBM50080288 CHEMBL81616::N-[2-(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-ethyl]-acetamide

SMILES CC(=O)NCCNc1nc(nc2[nH]c(C)c(C)c12)-c1ccccc1

InChI Key InChIKey=RHBHHAJRAODTML-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50080288   

TargetAdenosine receptor A1(Human)
Cadus Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50080288(N-[2-(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataKi:  12nMAssay Description:Inhibitory activity against binding of the [3H]DPCPX to human A1 receptor (hA1) radioligands using competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Cadus Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50080288(N-[2-(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataKi:  23nMAssay Description:Inhibitory activity against binding of the [3H]CGS-21680 to human A2a receptor (hA2a) radioligands using competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cadus Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50080288(N-[2-(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against membranes from yeast cells transformed with human A1 receptor (hA1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cadus Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50080288(N-[2-(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against binding of [3H]DPCPX to human A1 receptor (hA1) using competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Cadus Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50080288(N-[2-(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataIC50: 48nMAssay Description:Inhibitory activity against binding of [3H]CGS-21680 to human A2a receptor (hA2a) using competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Cadus Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50080288(N-[2-(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataIC50: 48nMAssay Description:Inhibitory activity against membranes from HEK293 cells stably expressing the human A2a receptor (hA2a)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed