BDBM50080503 3-{(S)-3-[(7-Methoxy-naphthalene-2-sulfonyl)-(1H-pyrazol-3-ylmethyl)-amino]-2-oxo-pyrrolidin-1-ylmethyl}-benzamidine::CHEMBL119964

SMILES COc1ccc2ccc(S(=O)(=O)N(Cc3ccn[nH]3)[C@H]3CCN(Cc4cccc(C(=N)N)c4)C3=O)cc2c1

InChI Key InChIKey=APIAEPVFPGPDTC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50080503   

TargetCoagulation factor X(Human)
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080503BDBM50080503(3-{(S)-3-[(7-Methoxy-naphthalene-2-sulfonyl)-(1H-p...)
Affinity DataKi:  21nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080503BDBM50080503(3-{(S)-3-[(7-Methoxy-naphthalene-2-sulfonyl)-(1H-p...)
Affinity DataKi:  1.08E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080503BDBM50080503(3-{(S)-3-[(7-Methoxy-naphthalene-2-sulfonyl)-(1H-p...)
Affinity DataKi:  1.39E+3nMAssay Description:Inhibitory activity against bovine pancreatic trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed