BDBM50080875 CHEMBL3421677

SMILES CC(=O)N[C@H]1Cc2c([nH]c3ccccc23)CN([C@H](Cc2ccc(F)cc2)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(N)=O)C1=O

InChI Key InChIKey=QQUKFDYXKAFEKI-UHFFFAOYSA-N

Data  4 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50080875   

TargetMelanocortin receptor 4(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080875BDBM50080875(CHEMBL3421677)
Affinity DataIC50: 6.5nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4 receptor expressed in HEK293 cells by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080875BDBM50080875(CHEMBL3421677)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human MC4 receptor expressed in HEK293 cells assessed as cAMP accumulation by luminescence counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080875BDBM50080875(CHEMBL3421677)
Affinity DataIC50: 167nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC5 receptor expressed in HEK293 cells by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080875BDBM50080875(CHEMBL3421677)
Affinity DataEC50:  226nMAssay Description:Activity at human MC1 receptor expressed in HEK293 cells assessed as cAMP accumulation by luminescence counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080875BDBM50080875(CHEMBL3421677)
Affinity DataIC50: 258nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1 receptor expressed in HEK293 cells by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080875BDBM50080875(CHEMBL3421677)
Affinity DataEC50:  4.11E+3nMAssay Description:Antagonist activity at human MC5 receptor expressed in HEK293 cells assessed as cAMP accumulation by luminescence counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080875BDBM50080875(CHEMBL3421677)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3 receptor expressed in HEK293 cells by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed