BDBM50081084 2-(4-{2-[4-(6-Amino-pyridin-2-yl)-phenyl]-ethyl}-piperazin-1-yl)-N-isopropyl-acetamide::CHEMBL87186

SMILES CC(C)NC(=O)CN1CCN(CCc2ccc(cc2)-c2cccc(N)n2)CC1

InChI Key InChIKey=GJKKUWOOEFFGOH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081084   

TargetNitric oxide synthase, brain(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081084(2-(4-{2-[4-(6-Amino-pyridin-2-yl)-phenyl]-ethyl}-p...)
Affinity DataIC50: 256nMAssay Description:Inhibitory activity against rat neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081084(2-(4-{2-[4-(6-Amino-pyridin-2-yl)-phenyl]-ethyl}-p...)
Affinity DataIC50: 330nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081084(2-(4-{2-[4-(6-Amino-pyridin-2-yl)-phenyl]-ethyl}-p...)
Affinity DataIC50: 815nMAssay Description:Inhibitory activity against human endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed