BDBM50081106 4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benzoimidazol-2-one::CHEMBL329398

SMILES Clc1cc(OCCNCc2ccccc2)c2[nH]c(=O)[nH]c2c1

InChI Key InChIKey=YKNNRQLCQGQFRB-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50081106   

TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081106(4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benz...)
Affinity DataKi:  0.25nMAssay Description:Inhibition of [3H]quinpirole binding to rat striatal membrane Dopamine receptor D2 without GTP and sodiumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081106(4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benz...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of [3H]spiperone binding to human Dopamine receptor D2 in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081106(4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benz...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of [3H]quinpirole binding to rat striatal membrane Dopamine receptor D2 without GTP and sodiumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081106(4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benz...)
Affinity DataKi:  7.40nMAssay Description:Inhibition of [3H]spiperone binding to human Dopamine receptor D3 in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081106(4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benz...)
Affinity DataKi:  16nMAssay Description:Inhibition of [3H]spiperone binding to human Dopamine receptor D4.4 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed