BDBM50081109 Benzyl-[2-(1H-indazol-4-yloxy)-ethyl]-amine::CHEMBL87137

SMILES C(COc1cccc2[nH]ncc12)NCc1ccccc1

InChI Key InChIKey=WYGBVOBBNUHWLX-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50081109   

TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081109(Benzyl-[2-(1H-indazol-4-yloxy)-ethyl]-amine | CHEM...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of [3H]quinpirole binding to rat striatal membrane Dopamine receptor D2 without GTP and sodiumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081109(Benzyl-[2-(1H-indazol-4-yloxy)-ethyl]-amine | CHEM...)
Affinity DataKi:  8.80nMAssay Description:Inhibition of [3H]spiperone binding to human Dopamine receptor D3 in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081109(Benzyl-[2-(1H-indazol-4-yloxy)-ethyl]-amine | CHEM...)
Affinity DataKi:  36nMAssay Description:Inhibition of [3H]quinpirole binding to rat striatal membrane Dopamine receptor D2 without GTP and sodiumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081109(Benzyl-[2-(1H-indazol-4-yloxy)-ethyl]-amine | CHEM...)
Affinity DataKi:  80nMAssay Description:Inhibition of [3H]spiperone binding to human Dopamine receptor D2 in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081109(Benzyl-[2-(1H-indazol-4-yloxy)-ethyl]-amine | CHEM...)
Affinity DataKi:  316nMAssay Description:Inhibition of [3H]spiperone binding to human Dopamine receptor D4.4 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed