BDBM50081235 3-substituted farnesyl diphosphate analogue::4-[(Z)-ethylidene]-8,12-dimethyl-(7E)-1,7,11-tridecatriene1-diphosphate (3-alFPP)

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6]-[#6]=[#6])=[#6]\[#6]-[#8]P([#8-])(=O)[#8]P([#8-])([#8-])=O

InChI Key InChIKey=PRWKMHYGHGUQCW-UHFFFAOYSA-K

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081235   

LigandPNGBDBM50081235(4-[(Z)-ethylidene]-8,12-dimethyl-(7E)-1,7,11-tride...)
Affinity DataIC50: 119nMAssay Description:Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
LigandPNGBDBM50081235(4-[(Z)-ethylidene]-8,12-dimethyl-(7E)-1,7,11-tride...)
Affinity DataIC50: 189nMAssay Description:Inhibition of recombinant farnesyltransferase (mFTase) in scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081235(4-[(Z)-ethylidene]-8,12-dimethyl-(7E)-1,7,11-tride...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant Geranylgeranyl transferase type I in scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed