BDBM50081515 4-Amino-3-[(S)-3-(5-methoxy-thieno[3,2-b]pyridine-2-sulfonylamino)-2-oxo-pyrrolidin-1-ylmethyl]-benzamidine::CHEMBL96218

SMILES COc1ccc2sc(cc2n1)S(=O)(=O)N[C@H]1CCN(Cc2cc(ccc2N)C(N)=N)C1=O

InChI Key InChIKey=ZENQPOAIMJIBQI-AWEZNQCLSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50081515   

TargetCoagulation factor X(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081515(4-Amino-3-[(S)-3-(5-methoxy-thieno[3,2-b]pyridine-...)
Affinity DataKi:  5nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081515(4-Amino-3-[(S)-3-(5-methoxy-thieno[3,2-b]pyridine-...)
Affinity DataKi:  210nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081515(4-Amino-3-[(S)-3-(5-methoxy-thieno[3,2-b]pyridine-...)
Affinity DataKi:  860nMAssay Description:Binding affinity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlasminogen(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081515(4-Amino-3-[(S)-3-(5-methoxy-thieno[3,2-b]pyridine-...)
Affinity DataKi: >7.30E+3nMAssay Description:Binding affinity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTissue-type plasminogen activator(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081515(4-Amino-3-[(S)-3-(5-methoxy-thieno[3,2-b]pyridine-...)
Affinity DataKi: >8.70E+3nMAssay Description:Binding affinity against tissue plasminogen activator (t-Pa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVitamin K-dependent protein C(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081515(4-Amino-3-[(S)-3-(5-methoxy-thieno[3,2-b]pyridine-...)
Affinity DataKi:  9.50E+3nMAssay Description:Binding affinity against activated protein C (APC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed