BDBM50081558 CHEMBL3422071

SMILES CN1CCC(Oc2ccc(-c3n[nH]c4ccc(C(=O)NC(c5ccccn5)C5CCCC5)cc34)cc2)CC1

InChI Key InChIKey=KTPMQAQBFZCIRN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081558   

TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50081558BDBM50081558(CHEMBL3422071)
Affinity DataIC50: 4nMAssay Description:Inhibition of amino terminal GST-fused full length human TTK using His6-SUMO-TTK-N as substrate preincubated for 15 mins prior to ATP addition by ind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50081558BDBM50081558(CHEMBL3422071)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of recombinant KDR (unknown origin) preincubated for 15 mins prior to ATP addition by FRET-based homogenous assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2016
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50081558BDBM50081558(CHEMBL3422071)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant AURKA (unknown origin) preincubated for 15 mins prior to ATP addition by FRET-based homogenous assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2016
Entry Details Article
PubMed