BDBM50081733 3-(3-Methyl-isoxazol-5-ylmethylene)-1-aza-bicyclo[2.2.2]octane::3-[1-(3-Methyl-isoxazol-5-yl)-meth-(Z)-ylidene]-1-aza-bicyclo[2.2.2]octane::CHEMBL58416
SMILES Cc1cc(\C=C2/CN3CCC2CC3)on1
InChI Key InChIKey=WJMKWBQPBBUJHD-YRNVUSSQSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50081733
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Institute of Science and Technology
Curated by ChEMBL
Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Compound was tested for its binding affinity against nicotinic receptor in synaptic membrane fractions from rat cerebral cortices.More data for this Ligand-Target Pair
Affinity DataIC50: 658nMAssay Description:In vitro displacement of [3H]oxotremorine-M from muscarinic acetylcholine receptor in rat brain cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration required for in vitro binding affinity to cholinergic central muscarinic receptor on rat brain cortex by using [3H]OXO-MMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibitory concentration required for in vitro binding affinity to Nicotinic acetylcholine receptor alpha3-beta2 expressed on cell line sf 9 by using...More data for this Ligand-Target Pair