BDBM50081803 CHEMBL94840::{1,1-Difluoro-2-[(3R,4R)-4-(6-oxo-1,6-dihydro-purin-9-ylmethyl)-tetrahydro-furan-3-yl]-ethyl}-phosphonic acid

SMILES OP(O)(=O)C(F)(F)C[C@H]1COC[C@H]1Cn1cnc2c1nc[nH]c2=O

InChI Key InChIKey=FXZULIFCFHYXFH-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081803   

TargetPurine nucleoside phosphorylase(Human)
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50081803({1,1-Difluoro-2-[(3R,4R)-4-(6-oxo-1,6-dihydro-puri...)
Affinity DataKi:  15nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in human erythrocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50081803({1,1-Difluoro-2-[(3R,4R)-4-(6-oxo-1,6-dihydro-puri...)
Affinity DataIC50: 35nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in Cellulomonas spMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50081803({1,1-Difluoro-2-[(3R,4R)-4-(6-oxo-1,6-dihydro-puri...)
Affinity DataIC50: 88nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in human erythrocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed