BDBM50082203 CHEMBL3422651
SMILES CC(C)Cn1cc(C#N)c2cc(Oc3ccc(NC(=O)[C@@H]4CCCN4)cc3)ccc12
InChI Key InChIKey=OOGHGWKBJXQNEJ-QFIPXVFZSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50082203
Affinity DataIC50: 384nMAssay Description:Inhibition of recombinant human PFKFB2 using fructose 6 phosphate as substrate assessed as ADP generation after 1 hr by ADP Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human PFKFB3 using fructose 6 phosphate as substrate assessed as ADP generation after 1 hr by ADP Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of recombinant human PFKFB1 using fructose 6 phosphate as substrate assessed as ADP generation after 1 hr by ADP Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.77E+3nMAssay Description:Inhibition of PFKFB3 in human A549 cells assessed as decrease in lactate secretion after 4 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 343nMAssay Description:Inhibition of PFKFB3 in human A549 cells assessed as reduction of fructose-1,6-bisphosphate formation after 4 hrs by MS/MS analysisMore data for this Ligand-Target Pair