BDBM50082370 3-(Benzo[b]thiophen-5-yloxy)-4-(4-methanesulfonyl-phenyl)-5,5-dimethyl-5H-furan-2-one::CHEMBL108512

SMILES CC1(C)OC(=O)C(Oc2ccc3sccc3c2)=C1c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=GJJZKGZYUTXFMK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082370   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50082370(3-(Benzo[b]thiophen-5-yloxy)-4-(4-methanesulfonyl-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of PGE-2 production in CHO cells expressing human COX-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50082370(3-(Benzo[b]thiophen-5-yloxy)-4-(4-methanesulfonyl-...)
Affinity DataIC50:  80nMAssay Description:Inhibitory potency against PGE-2 production in the human whole blood (HWB COX-2) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50082370(3-(Benzo[b]thiophen-5-yloxy)-4-(4-methanesulfonyl-...)
Affinity DataIC50: <300nMAssay Description:Inhibition of PGE-2 production in CHO cells expressing human COX-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed