BDBM50082559 (S)-7-(4-Methoxy-benzenesulfonyl)-5,5-dimethyl-4,4-dioxo-4lambda*6*-[1,4,7]oxathiazonane-6-carboxylic acid hydroxyamide::CHEMBL421932

SMILES COc1ccc(cc1)S(=O)(=O)N1CCOCCS(=O)(=O)C(C)(C)[C@@H]1C(=O)NO

InChI Key InChIKey=ZHLANTZRDCBWFM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50082559   

TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082559((S)-7-(4-Methoxy-benzenesulfonyl)-5,5-dimethyl-4,4...)
Affinity DataIC50: 1.90nMAssay Description:In vitro inhibitory activity against truncated collagenase-1 (matrix metalloprotease-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082559((S)-7-(4-Methoxy-benzenesulfonyl)-5,5-dimethyl-4,4...)
Affinity DataIC50: 3.30nMAssay Description:In vitro inhibitory activity against collagenase-3 (matrix metalloprotease-13).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082559((S)-7-(4-Methoxy-benzenesulfonyl)-5,5-dimethyl-4,4...)
Affinity DataIC50: 45nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082559((S)-7-(4-Methoxy-benzenesulfonyl)-5,5-dimethyl-4,4...)
Affinity DataIC50: 183nMAssay Description:In vitro inhibitory activity against matrilysin (matrix metalloprotease-7).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed