BDBM50082563 (R)-4-(4-Methoxy-benzenesulfonyl)-3-methyl-[1,4]thiazepane-3-carboxylic acid hydroxyamide::CHEMBL141451

SMILES COc1ccc(cc1)S(=O)(=O)N1CCCSC[C@@]1(C)C(=O)NO

InChI Key InChIKey=GFDLNQRSUGRRNQ-AWEZNQCLSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50082563   

TargetMatrilysin(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082563((R)-4-(4-Methoxy-benzenesulfonyl)-3-methyl-[1,4]th...)
Affinity DataIC50:  1.77E+4nMAssay Description:In vitro inhibitory activity against matrilysin (matrix metalloprotease-7).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082563((R)-4-(4-Methoxy-benzenesulfonyl)-3-methyl-[1,4]th...)
Affinity DataIC50:  4.20nMAssay Description:In vitro inhibitory activity against gelatinase-A (matrix metalloprotease-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082563((R)-4-(4-Methoxy-benzenesulfonyl)-3-methyl-[1,4]th...)
Affinity DataIC50:  31nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082563((R)-4-(4-Methoxy-benzenesulfonyl)-3-methyl-[1,4]th...)
Affinity DataIC50:  217nMAssay Description:In vitro inhibitory activity against truncated collagenase-1 (matrix metalloprotease-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082563((R)-4-(4-Methoxy-benzenesulfonyl)-3-methyl-[1,4]th...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibitory activity against collagenase-3 (matrix metalloprotease-13).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed