BDBM50082580 3,3-Dimethyl-1,2,3,4-tetrahydro-quinoline-8-sulfonic acid {4-guanidino-1-[4-(2-hydroxy-ethyl)-piperidine-1-carbonyl]-butyl}-amide::CHEMBL448420

SMILES CC1(C)CNc2c(C1)cccc2S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCC(CCO)CC1

InChI Key InChIKey=KKYOZZAUCIMAQW-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50082580   

TargetProthrombin(Bovine)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50082580(3,3-Dimethyl-1,2,3,4-tetrahydro-quinoline-8-sulfon...)
Affinity DataKi:  32nMAssay Description:The compound was evaluated for the inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Bovine)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50082580(3,3-Dimethyl-1,2,3,4-tetrahydro-quinoline-8-sulfon...)
Affinity DataKi:  48nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAnionic trypsin(Bovine)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50082580(3,3-Dimethyl-1,2,3,4-tetrahydro-quinoline-8-sulfon...)
Affinity DataKi:  7.10E+3nMAssay Description:The compound was evaluated for the inhibitory activity against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetChymotrypsinogen A(Bovine)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50082580(3,3-Dimethyl-1,2,3,4-tetrahydro-quinoline-8-sulfon...)
Affinity DataKi:  8.30E+4nMAssay Description:The compound was evaluated for the inhibitory activity against bovine ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlasminogen(Human)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50082580(3,3-Dimethyl-1,2,3,4-tetrahydro-quinoline-8-sulfon...)
Affinity DataKi:  2.10E+5nMAssay Description:The compound was evaluated for the inhibitory activity against human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed