BDBM50082678 5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2-(3-hydroxy-phenyl)-pentanenitrile::CHEMBL341840

SMILES Oc1cccc(c1)C(CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)C#N

InChI Key InChIKey=WEYKBNXSBLQOIY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082678   

TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50082678(5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2...)
Affinity DataKi:  156nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to recombinant human C-C chemokine receptor type 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50082678(5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of MIP-1-alpha-induced intracellular calcium mobilization in HEK293 cells expressing human CCR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed