BDBM50082688 5-{3-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-propyl}-10,11-dihydro-5H-dibenzo[a,d]cycloheptene-5-carbonitrile::CHEMBL433746

SMILES OC1(CCN(CCCC2(C#N)c3ccccc3CCc3ccccc23)CC1)c1ccc(Cl)cc1

InChI Key InChIKey=HLJAUIIGTPYTIX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082688   

TargetC-C chemokine receptor type 1(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50082688(5-{3-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl...)
Affinity DataKi:  45nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to recombinant human C-C chemokine receptor type 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50082688(5-{3-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of MIP-1-alpha-induced intracellular calcium mobilization in HEK293 cells expressing human CCR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed