BDBM50083438 CHEMBL424509::[1-(3-Benzyl-3H-imidazol-4-ylmethyl)-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-naphthalen-1-yl-methanone

SMILES O=C(N1CCN(Cc2cncn2Cc2ccccc2)c2ccccc2C1)c1cccc2ccccc12

InChI Key InChIKey=VAAZAFPELPRBBL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083438   

TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083438(CHEMBL424509 | [1-(3-Benzyl-3H-imidazol-4-ylmethyl...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed