BDBM50083534 1-Methyl-4-naphthalen-2-yl-piperidine-4-carboxylic acid ethyl ester::CHEMBL419744::CHEMBL536952

SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc2ccccc2c1

InChI Key InChIKey=CVAPXJCGJFOSDW-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50083534   

TargetSodium-dependent serotonin transporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083534(1-Methyl-4-naphthalen-2-yl-piperidine-4-carboxylic...)
Affinity DataKi:  7.20nMAssay Description:Displacement of [3H]-paroxetine from serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083534(1-Methyl-4-naphthalen-2-yl-piperidine-4-carboxylic...)
Affinity DataKi:  7.20nMAssay Description:Displacement of [3H]citalopram from serotonin transporter in Sprague-Dawley rat brain after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083534(1-Methyl-4-naphthalen-2-yl-piperidine-4-carboxylic...)
Affinity DataKi:  7.20nMAssay Description:Inhibition of [3H]paroxetine binding to rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083534(1-Methyl-4-naphthalen-2-yl-piperidine-4-carboxylic...)
Affinity DataKi:  1.14E+3nMAssay Description:Displacement of [3H]-WIN- 35,428 from dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083534(1-Methyl-4-naphthalen-2-yl-piperidine-4-carboxylic...)
Affinity DataKi:  1.14E+3nMAssay Description:Displacement of [3H]WIN 35428 from dopamine transporter in Sprague-Dawley rat brain after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083534(1-Methyl-4-naphthalen-2-yl-piperidine-4-carboxylic...)
Affinity DataKi:  1.14E+3nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083534(1-Methyl-4-naphthalen-2-yl-piperidine-4-carboxylic...)
Affinity DataKi:  2.03E+3nMAssay Description:Inhibition of [3H]DAMGO binding to mu-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083534(1-Methyl-4-naphthalen-2-yl-piperidine-4-carboxylic...)
Affinity DataKi:  7.10E+4nMAssay Description:Displacement of [3H]nisoxetine from norepinephrine transporter in Sprague-Dawley rat frontal cortex after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083534(1-Methyl-4-naphthalen-2-yl-piperidine-4-carboxylic...)
Affinity DataKi:  7.11E+4nMAssay Description:Inhibition of [3H]-nisoxetine binding to rat norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed