BDBM50083636 4-[(1-Allyl-3-methyl-piperidin-4-yl)-phenyl-amino]-N,N-diethyl-benzamide::CHEMBL115730

SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CC=C)CC1C)c1ccccc1

InChI Key InChIKey=DZIVFTSZIVQCKX-UHFFFAOYSA-N

Data  3 KI  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50083636   

TargetDelta-type opioid receptor(Mouse)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50083636(4-[(1-Allyl-3-methyl-piperidin-4-yl)-phenyl-amino]...)
Affinity DataKi:  12nMAssay Description:Binding affinity towards opioid Delta receptor using [3H]DADLE as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50083636(4-[(1-Allyl-3-methyl-piperidin-4-yl)-phenyl-amino]...)
Affinity DataKi:  1.21E+3nMAssay Description:Binding affinity towards opioid Mu receptor using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50083636(4-[(1-Allyl-3-methyl-piperidin-4-yl)-phenyl-amino]...)
Affinity DataKi:  3.28E+3nMAssay Description:Binding affinity towards opioid kappa receptor using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50083636(4-[(1-Allyl-3-methyl-piperidin-4-yl)-phenyl-amino]...)
Affinity DataKd:  3.50E+3nMAssay Description:Binding affinity against Mu opioid receptor using [35S]GTP-gamma-S, binding assay in guinea pig caudate membranes blocked with 6000 nM CTAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50083636(4-[(1-Allyl-3-methyl-piperidin-4-yl)-phenyl-amino]...)
Affinity DataKd:  3.72E+3nMAssay Description:Binding affinity against kappa opioid receptor using [35S]GTP-gamma-S, binding assay in guinea pig caudate membranes blocked with 6 nM nor-BNIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50083636(4-[(1-Allyl-3-methyl-piperidin-4-yl)-phenyl-amino]...)
Affinity DataKd:  4.67E+3nMAssay Description:Binding affinity against Mu opioid receptor using [35S]GTP-gamma-S, binding assay in guinea pig caudate membranes blocked with 6000 nM CTAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed