BDBM50084203 (R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-ethoxyimino]-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL440355

SMILES CCCCOc1ccc(cc1)S(=O)(=O)N1C\C(C[C@@H]1C(=O)NO)=N/OCC

InChI Key InChIKey=XJMLKUIRAXOATH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084203   

TargetCollagenase 3(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084203((R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-ethoxyimin...)
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of human recombinant collagenase-3 (Matrix metalloprotease-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084203((R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-ethoxyimin...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibition activity of human recombinant stromelysin (Matrix metalloprotease-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084203((R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-ethoxyimin...)
Affinity DataIC50: 39nMAssay Description:In vitro inhibition of matrilysin (Matrix metalloprotease-7, MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084203((R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-ethoxyimin...)
Affinity DataIC50: 39nMAssay Description:In vitro inhibition of human recombinant collagenase-1 (Matrix metalloprotease-1, MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed