BDBM50084206 (R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-methoxyimino]-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL149977

SMILES CCCCOc1ccc(cc1)S(=O)(=O)N1C\C(C[C@@H]1C(=O)NO)=N/OC

InChI Key InChIKey=OCZKLINSAMKTBK-PWDRBQJJSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084206   

TargetMatrilysin(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084206((R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-methoxyimi...)
Affinity DataIC50:  89nMAssay Description:In vitro inhibition of matrilysin (Matrix metalloproteinase-7, MMP-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084206((R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-methoxyimi...)
Affinity DataIC50:  0.300nMAssay Description:In vitro inhibition of human recombinant collagenase-3 (Matrix metalloproteinase-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterstitial collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084206((R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-methoxyimi...)
Affinity DataIC50:  26nMAssay Description:In vitro inhibition of human recombinant collagenase-1 (Matrix metalloproteinase-1, MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084206((R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-methoxyimi...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibition activity of human recombinant stromelysin (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed